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PEDIATRIC MULTI SYSTEM INFLAMMATORY SYNDROME

PEDIATRIC MULTI SYSTEM INFLAMMATORY SYNDROME ASSOCIATED WITH COVID 19 

  • Recently a possible link has been reported between COVID-19 and Pediatric Multi-System Inflammatory Syndrome (PMIS) temporally associated with COVID-19.
  • As of May 12th, 102 suspect cases of PMIS have been reported by hospitals in New York State and are under investigation by the New York State Department of Health.

Clinical Criteria: An individual aged < 21 years with:

  • A minimum one-day history of subjective OR objective fever (≥ 100.4° F/38° C); AND
  • Hospitalization; AND
  • Either

        One or more of the following:

  • Hypotension or shock (cardiogenic or vasogenic)
  • Features of severe cardiac illness including but not limited to myocarditis, pericarditis, or valvulitis, significantly elevated                     troponin/pro-BNP, or coronary artery abnormalities
  • Other severe end-organ involvement including but not limited to neurological or renal disease (excluding severe respiratory               disease alone)

       OR

          Two or more of the following:

  • Maculopapular rash
  • Bilateral non-purulent conjunctivitis
  • Mucocutaneous inflammatory signs (mouth, hands, or feet)
  • Acute gastrointestinal symptoms (diarrhea, vomiting, or abdominal pain); AND
  • The absence of a more likely diagnosis of the illness, e.g., bacterial sepsis or other viral infection.   

 

Epidemiologic Criteria:
One or more of the following exposures in the 6 weeks prior to the onset of symptoms:

  • Close contact with an individual with laboratory-confirmed SARS-CoV-2 infection.1
  • Close contact with an individual with illness clinically compatible with COVID-19 disease who had close contact with an individual with laboratory-confirmed SARS-CoV-2 infection.1
  • Travel to or residence in an area with sustained, ongoing community transmission of SARS-CoV-2.

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